The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2013
Filed:
Apr. 30, 2009
Virgil Percec, Philadelphia, PA (US);
Brad Matthew Rosen, Philadelphia, PA (US);
Daniela A. Wilson, Rotherham, GB;
Christopher J. Wilson, Rotherham, GB;
Virgil Percec, Philadelphia, PA (US);
Brad Matthew Rosen, Philadelphia, PA (US);
Daniela A. Wilson, Rotherham, GB;
Christopher J. Wilson, Rotherham, GB;
The Trustees Of The University Of Pennsylvania, Philadelphia, PA (US);
Abstract
The invention concerns processes for the synthesis of a compound of the formula: wherein: Rand Rare each, independently, C-Calkyl, COR, OR, R(OR), or C-Caryl; R-Rare each, independently, C-Calkyl or C-Caryl; and n and m are each, independently, O or an integer from 1-5; said process comprising:—contacting a compound of the formula H0-R-0H with BHand a compound of the formula in the presence of a nickel-containing catalyst to produce a first product, where Ris a C-Chydrocarbon group and X is a halogen, OMs or OTs;—contacting the first product in situ with a compound of the formula: in the presence of a nickel-containing catalyst to produce a compound of formula I, where Z is a halogen.