The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2013
Filed:
Oct. 27, 2010
Applicants:
Chi Ming Che, Hong Kong, CN;
Raymond Wai-yin Sun, Hong Kong, CN;
Lok Fung Chow, Hong Kong, CN;
Jing Yan, Hong Kong, CN;
Inventors:
Chi Ming Che, Hong Kong, CN;
Raymond Wai-Yin Sun, Hong Kong, CN;
Lok Fung Chow, Hong Kong, CN;
Jing Yan, Hong Kong, CN;
Assignee:
The University of Hong Kong, Hong Kong, HK;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/555 (2006.01); C07F 1/12 (2006.01); C07F 15/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present disclosure is related to a pharmaceutical composition for treatment of cancer comprising a cyclometalated N-heterocyclic carbene complex. The cyclometalated N-heterocyclic carbene complex contains a gold(III) or a platinum(II) atom. The pharmaceutical composition possesses anti-cancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of topoisomerase and/or poisoning of topoisomerase.