The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2013
Filed:
Jan. 14, 2008
Mark Ginsberg, San Diego, CA (US);
Anthony William Partridge, Montreal, CA;
Iain Campbell, Oxford, GB;
Kate Louise Wegener, Adelaide, AU;
Mark Ginsberg, San Diego, CA (US);
Anthony William Partridge, Montreal, CA;
Iain Campbell, Oxford, GB;
Kate Louise Wegener, Adelaide, AU;
The Regents of the University of California, Oakland, CA (US);
Abstract
The specific molecular basis of the interaction between talin and integrin βhas been defined. This specific interaction provides a new therapeutic target; agents that can disrupt this specific interaction should be useful therapeutic agents for a number of significant diseases and conditions including inflammation, heart disease, including myocardial infarction, and tumor metastasis. The present invention includes a chimeric peptide that has high affinity for talin, muteins of talin and integrin βas well as screening methods for agents that can disrupt the interaction between talin and integrin β.