The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2013
Filed:
Oct. 07, 2010
Kogyoku Shin, Hatfield, GB;
Taro Terauchi, Tsukuba, JP;
Yoshinori Takahashi, Tsukuba, JP;
Minako Hashizume, Tsukuba, JP;
Kunitoshi Takeda, Tsukuba, JP;
Kodo Shikata, Hatfield, GB;
Akira Inomata, Tsukuba, JP;
Kogyoku Shin, Hatfield, GB;
Taro Terauchi, Tsukuba, JP;
Yoshinori Takahashi, Tsukuba, JP;
Minako Hashizume, Tsukuba, JP;
Kunitoshi Takeda, Tsukuba, JP;
Kodo Shikata, Hatfield, GB;
Akira Inomata, Tsukuba, JP;
Eisai R&D Management Co., Ltd., Tokyo, JP;
Abstract
A compound represented by the formula (I) or pharmacologically acceptable salt thereof exhibits an excellent CRF receptor antagonism wherein X is a nitrogen atom or CH; Ris -A-A; Ais a single bond or a C1-6 alkylene group; Ais a hydrogen atom, a C1-6 alkyl group or a C3-6 cycloalkyl group, etc.; Ris -A-A; Ais a single bond or a C1-6 alkylene group; Ais a hydrogen atom, a C1-6 alkyl group, a C3-6 cycloalkyl group, a non-aromatic heterocyclic group, or a heteroaryl group, etc.; Ris a C1-6 alkyl group, a C3-6 cycloalkyl group, a C1-6 alkoxy group, a C3-6 cycloalkoxy C1-6 alkyl group, di-C1-6 alkyl amino group, a halogen atom, a cyano group, a formyl group, or a carboxyl group, etc; Ris a hydrogen atom or a C1-6 alkoxy group; Ris a halogen atom, a C1-6 alkyl group, or a C1-6 alkoxy group; Ris a hydrogen atom, a C1-6 alkyl group, a C1-6 alkoxy group, a C1-6 alkylthio group, or a C1-6 alkyl sulfinyl group etc.; and Ris a C1-6 alkyl group, a C1-6 alkoxy group, or a C1-6 alkylthio group.