The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2013
Filed:
Oct. 08, 2008
Yongyuth Yuthavong, Klong Luang, TH;
Tirayut Vilaivan, Patumwan, TH;
Sumalee Kamchonwongpaisan, Klong Luang, TH;
Bongkoch Tarnchompoo, Klong Luang, TH;
Chawanee Thongpanchang, Klong Luang, TH;
Penchit Chitnumsub, Klong Luang, TH;
Jirundon Yuvaniyama, Ratchathewi, TH;
David Matthews, Encinitas, CA (US);
William Charman, Parkville, AU;
Susan Charman, Parkville, AU;
Livia Vivas, Keppel, GB;
Sanjay Babu Katiyar, Salt Lake, IN;
Yongyuth Yuthavong, Klong Luang, TH;
Tirayut Vilaivan, Patumwan, TH;
Sumalee Kamchonwongpaisan, Klong Luang, TH;
Bongkoch Tarnchompoo, Klong Luang, TH;
Chawanee Thongpanchang, Klong Luang, TH;
Penchit Chitnumsub, Klong Luang, TH;
Jirundon Yuvaniyama, Ratchathewi, TH;
David Matthews, Encinitas, CA (US);
William Charman, Parkville, AU;
Susan Charman, Parkville, AU;
Livia Vivas, Keppel, GB;
Sanjay Babu Katiyar, Salt Lake, IN;
Medicines for Malaria Venture (MMV), Geneva, CH;
Abstract
The present invention relates to novel compounds that are inhibitors of wild type and mutant dihydrofolate reductase (DHFR) of, which are useful for the treatment of malaria. It also relates to processes of making and using such compounds. The antimalarial compounds of the present invention have low toxicity to a host infected with the malarial parasite, and are potent when administered in pharmaceutical compositions.