The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2013
Filed:
Oct. 12, 2011
Gianni Chessari, Cambridge, GB;
Miles Stuart Congreve, Cambridge, GB;
Martyn Frederickson, Cambridge, GB;
Christopher William Murray, Cambridge, GB;
Eva Figueroa Navarro, Cambridge, GB;
Alison Jo-anne Woolford, Cambridge, GB;
Maria Grazia Carr, Luton, GB;
Robert Downham, Cambridge, GB;
Michael Alistair O'brien, Herts, GB;
Theresa Rachel Phillips, Macclesfield, GB;
Andrew James Woodhead, Cambridge, GB;
Gianni Chessari, Cambridge, GB;
Miles Stuart Congreve, Cambridge, GB;
Martyn Frederickson, Cambridge, GB;
Christopher William Murray, Cambridge, GB;
Eva Figueroa Navarro, Cambridge, GB;
Alison Jo-Anne Woolford, Cambridge, GB;
Maria Grazia Carr, Luton, GB;
Robert Downham, Cambridge, GB;
Michael Alistair O'Brien, Herts, GB;
Theresa Rachel Phillips, Macclesfield, GB;
Andrew James Woodhead, Cambridge, GB;
Astex Therapeutics Ltd., Cambridge, GB;
Abstract
The invention provides a combination comprising an Hsp90 inhibitor compound of the formula (VII): or tautomer or salt thereof and one or more therapeutic agents selected from topoisomerase I inhibitors; antimetabolites; tubulin targeting agents; DNA binder and topoisomerase II inhibitors; alkylating agents; monoclonal antibodies; anti-hormones; signal transduction inhibitors; proteasome inhibitors; DNA methyl transferases; cytokines; retinoids and HDAC or HAT modulators.