The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2013
Filed:
Mar. 21, 2005
Applicants:
Michael A. Caligiuri, Columbus, OH (US);
Rossana Trotta, Dublin, OH (US);
Jianhua Yu, Columbus, OH (US);
Brian Becknell, Westerville, OH (US);
Inventors:
Michael A. Caligiuri, Columbus, OH (US);
Rossana Trotta, Dublin, OH (US);
Jianhua Yu, Columbus, OH (US);
Brian Becknell, Westerville, OH (US);
Assignee:
The Ohio State University Research Foundation, Columbus, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
Methods for stably transfecting mammalian natural killer cells comprising: transfecting a packaging cell line with a retroviral expression vector; culturing the transfected packaging cell line in a cell culture medium; and culturing the mammalian natural killer cells with the cell culture medium. Natural killer cells transfected according to the disclosed methods are also provided.