The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2013
Filed:
Jul. 11, 2007
Tobias Schroder, Somerville, MA (US);
Marcos F. Vidal Melo, Newton, MA (US);
Guido Musch, Somerville, MA (US);
Robert Scott Harris, Wayland, MA (US);
Jose G. Venegas, Swampscott, MA (US);
Tilo Winkler, Brookline, MA (US);
Tobias Schroder, Somerville, MA (US);
Marcos F. Vidal Melo, Newton, MA (US);
Guido Musch, Somerville, MA (US);
Robert Scott Harris, Wayland, MA (US);
Jose G. Venegas, Swampscott, MA (US);
Tilo Winkler, Brookline, MA (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
An input function indicative of a time-activity curve in pulmonary arterial plasma is produced from a series of PET image frames in lieu of manual blood sampling. Two manually acquired blood samples are input along with pixel values of a blood pool region of interest (ROI) in the PET image frames into a two-parameter model of the ROI's time-activity curve. In an iterative process the model converges to accurately indicate the amount ofF-FDG tracer in the arterial blood. Pulmonary uptake of the tracer is assessed with the PET image frames and the calculated input function.