The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 03, 2013

Filed:

Dec. 20, 2012
Applicant:

Mochida Pharmaceutical Co., Ltd., Tokyo, JP;

Inventors:

Hiroshi Takayama, Ibaraki, JP;

Kamon Shirakawa, Tokyo, JP;

Shoji Furusako, Tokyo, JP;

Yoshitaka Hosaka, Tokyo, JP;

Tomokazu Matsusue, Tokyo, JP;

Katsuki Naitoh, Tokyo, JP;

Yumi Hotta, Tokyo, JP;

Tetsushi Kawahara, Tokyo, JP;

Motoyasu Honda, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides an antibody which has the following features, its active fragment, or a derivative thereof: a) It specifically binds to human platelet membrane glycoprotein VI (GPVI); b) The function to activate a platelet and/or the function to induce a thrombocytopenia in vivo are low; and c) It at least partially depletes GPVI on the platelet membrane by contacting with a platelet.


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