The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2013
Filed:
Oct. 06, 2009
Stewart Douglas Nuttall, Victoria, AU;
Victor Anatolievich Streltsov, Victoria, AU;
Joseph Noozhumurry Varghese, Victoria, AU;
Vidanagamage Chandana Epa, Victoria, AU;
Stewart Douglas Nuttall, Victoria, AU;
Victor Anatolievich Streltsov, Victoria, AU;
Joseph Noozhumurry Varghese, Victoria, AU;
Vidanagamage Chandana Epa, Victoria, AU;
Commonwealth Scientific and Industrial Research Organisation, Campbell, AU;
Abstract
The invention relates provides a novel crystal structure of the fibrillogenic part of amyloid β-peptide (Aβ). More specifically the crystal structure is Aβ-IgNAR and, accordingly the present invention also relates to selecting and/or designing compounds that modulate amyloid β-peptide (Aβ) activity using techniques such as in silico screening and crystal soaking experiments. The invention further relates to compounds and methods for inhibiting interaction between amyloid β-peptide (Aβ) monomers, more particularly, inhibiting or disrupting amyloid β-peptide (Aβ) oligomer formation and toxic activity.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile