The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2013
Filed:
Jan. 21, 2011
Gottumukkala V. Subbaraju, Tirupati, IN;
Masna Mahesh, Hyderabad, IN;
Hindupur R. Mohan, Hyderabad, IN;
Thatipally Suresh, Hyderabad, IN;
Igor Ivanisevic, West Lafayette, IN (US);
Mark Andres, West Lafayette, IN (US);
Kyle Stephens, Farmland, IN (US);
Gottumukkala V. Subbaraju, Tirupati, IN;
Masna Mahesh, Hyderabad, IN;
Hindupur R. Mohan, Hyderabad, IN;
Thatipally Suresh, Hyderabad, IN;
Igor Ivanisevic, West Lafayette, IN (US);
Mark Andres, West Lafayette, IN (US);
Kyle Stephens, Farmland, IN (US);
Laurus Labs Private Limited, , IN;
Abstract
The present invention provides a scalable process for the preparation of stilbenes by (i) condensing 3,5-dialkylbenzyl phosphonates with 4'-O-tetrahydropyranyl benzaldehyde to get 3,5-alkyl-4′-O-tetrahydropyranyl Stilbene and (ii) deprotecting the obtained 3,5-Dialkyl-4′-O-tetrahydropyranylstilbene to yield stilbenes. The present invention also provides a novel intermediate 3,5-Dialkyl-4′-O-tetrahydropyranyl stilbene, which is a key intermediate for the synthesis of stilbenes such as Pterostilbene and Resveratrol. The present invention also provides characteristics of various solid forms of Pterostilbene, methods for their preparation, as well as dosage forms containing the same for administration to or consumption by humans.