Organosulfur compounds, a method of making organosulfur compounds and their use for inhibiting the growth of tumour cells

Abstract

Organosulfur compounds of the general formula (2) are described, wherein Rand Rare linear or branched C1-C5 alkyl; linear or branched C1-C5 alkenyl with the proviso that Ris not prop-1-enyl (allyl); substituted linear or branched C1-C5 alkenyl or substituted linear or branched C1-C5 alkyl, in which the substituents are selected from OR, NRR, COOR, CON—RR, in which Ris selected from H, COR, para-methoxybenzyl and trialkylsilyl, in which Ris alkyl or substituted alkyl; RN and Rare alkyl or Rand Rtogether form a phthalimido group; Ris alkyl or substituted alkyl; and Rand Rare alkyl or substituted alkyl; substituted or unsubstituted aromatic specifically where Rand Rare benzyl, para-methoxybenzyl and/or ortho,para-methoxybenzyl and substituted or unsubstituted heteroaromatic. The compounds can be used for inhibiting the growth of tumor cells and for treating cancer. A pharmaceutical composition and a method of preparing the compounds are also described.