The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2013
Filed:
Aug. 31, 2009
David Brown, Austin, TX (US);
Lance P. Ford, Austin, TX (US);
Richard A. Jarvis, Austin, TX (US);
Vince Pallotta, Austin, TX (US);
Brittan L. Pasloske, Austin, TX (US);
David Brown, Austin, TX (US);
Lance P. Ford, Austin, TX (US);
Richard A. Jarvis, Austin, TX (US);
Vince Pallotta, Austin, TX (US);
Brittan L. Pasloske, Austin, TX (US);
Applied Biosystems, LLC, Carlsbad, CA (US);
Abstract
The present invention provides improved methods of attenuating gene expression through the phenomenon of RNA interference. The invention provides methods of synthesis of double stranded RNAs (dsRNAs) of increased potency for use as small interfering RNA (siRNA). Surprisingly and unexpectedly, siRNAs made by the methods of the invention are significantly more potent than previously available siRNAs.