The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2013
Filed:
Jul. 02, 2010
Chu Won Nho, Gangneung-si, KR;
NA Ra Jeon, Gangnueng-si, KR;
Kyung Su Kang, Gangneung-si, KR;
Saet Byoul Lee, Gangneung-si, KR;
Ji Hye Yoo, Gwangmyeong-si, KR;
Suk Woo Kang, Gangneung-si, KR;
Byung Hun Um, Gangneung-si, KR;
Cheol-ho Pan, Gangneung-si, KR;
Chu Won Nho, Gangneung-si, KR;
Na Ra Jeon, Gangnueng-si, KR;
Kyung Su Kang, Gangneung-si, KR;
Saet Byoul Lee, Gangneung-si, KR;
Ji Hye Yoo, Gwangmyeong-si, KR;
Suk Woo Kang, Gangneung-si, KR;
Byung Hun Um, Gangneung-si, KR;
Cheol-Ho Pan, Gangneung-si, KR;
Korea Institute of Science and Technology, Seoul, KR;
Abstract
The present invention relates to a method for the prevention and treatment of postmenopausal syndrome containing the step of administering a pharmaceutically effective dose of theor its fractions to a subject. The present inventors confirmed that theextract or its fractions of the invention prepared by using water, alcohol or a mixed solvent thereof could promote the expression of the promoter containing estrogen responsive element (ERE) and accelerated the growth of MCF-7, the human breast tissue originated cell line, suggesting that they had estrogen activity. The inventors further confirmed that the extract or its fractions of the invention had the effect of promoting osteocyte differentiation, so that they could be effectively used for the prevention and treatment of postmenopausal syndrome such as hot flush, osteoporosis and phlebothrombosis caused by estrogen deficiency.