The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8519168 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 27, 2013

Filed:

Jul. 01, 2008
Applicants:

Xiaoyong Fu, Edison, NJ (US);

Frank Bruno Guenter, Ruswil, CH;

Agnes S. Kim-meade, Fanwood, NJ (US);

Kenneth Stanley Matthews, Stockton, CA (US);

Mathew Thomas Maust, Westfield, NJ (US);

Gerald Werne, Ketsch, DE;

Jason L. Winters, East Windsor, NJ (US);

Jianguo Yin, Plainsboro, NJ (US);

Shuyi Zhang, Parsippany, NJ (US);

David J. Moloznik, Philadelphia, PA (US);

Inventors:

Xiaoyong Fu, Edison, NJ (US);

Frank Bruno Guenter, Ruswil, CH;

Agnes S. Kim-Meade, Fanwood, NJ (US);

Kenneth Stanley Matthews, Stockton, CA (US);

Mathew Thomas Maust, Westfield, NJ (US);

Timothy L. McAllister, Westfield, NJ (US);

Gerald Werne, Ketsch, DE;

Jason L. Winters, East Windsor, NJ (US);

Jianguo Yin, Plainsboro, NJ (US);

Shuyi Zhang, Parsippany, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/40 (2006.01);
U.S. Cl.
CPC ...
Abstract

This application discloses a novel process for the preparation of 1,2-substituted 3,4-dioxo-1-cyclobutene compounds, which have utility, for example, in the treatment of CXC chemokine-mediated diseases, and intermediates useful in the synthesis thereof.


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