The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2013

Filed:

Oct. 28, 2011
Applicants:

Laxmikant A. Gharat, Thane, IN;

Nagarajan Muthukaman, Erode, IN;

Lakshminarayana Narayana, Navi Mumbai, IN;

Neelima Khairatkar-joshi, Thane, IN;

Vidya G. Kattige, Thane, IN;

Inventors:

Laxmikant A. Gharat, Thane, IN;

Nagarajan Muthukaman, Erode, IN;

Lakshminarayana Narayana, Navi Mumbai, IN;

Neelima Khairatkar-Joshi, Thane, IN;

Vidya G. Kattige, Thane, IN;

Assignee:

Glenmark Pharmaceuticals S.A., La Chaux-de-Fonds, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/424 (2006.01); A61K 31/429 (2006.01); A61K 31/4188 (2006.01); C07D 491/048 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to tricyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.


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