The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2013
Filed:
Oct. 02, 2002
Claudio Giordano, Milan, IT;
Luca Giannini, Pavia, IT;
Claudio Giordano, Milan, IT;
Luca Giannini, Pavia, IT;
Euticals Prime European Therapeuticals SpA, Lodi, IT;
Abstract
A method is described for the preparation of aryl-pyridine compounds of formula (I) by cross-coupling reaction, promoted by catalytic systems based on palladium or nickel between compounds of formula (II) and (III) in which: -Met represents Mg or Zn, —Y represents Cl, Br, I or acetoxy, —Z represents I, Br, Cl, triflate, sulphonate, phosphate, —R, R, R, R, which are the same as one another or different, represent hydrogen, a linear and/or branched C-Calkyl, and/or an aryl, and/or a heteroaryl, or Rand Rand/or Rand R, taken together, form a C-Cring, an aryl and/or a heteroaryl, -A represents —CORwhere Rrepresents hydrogen, a linear and/or branched C-Calkyl, and/or an aryl, and/or a heteroaryl, or -A represents —CR(OR)(OR) where Rhas the meaning described above and Rand R, which are the same as one another or different, represent a linear and/or branched C-Calkyl, and/or an aryl, and/or a heteroaryl, or Rand R, joined together, represent a C-Calkyl or alkenyl.