The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2013
Filed:
Sep. 26, 2011
Applicants:
Ramachandran Radhakrishnan, Fremont, CA (US);
Michael Cyr, League City, TX (US);
Sabine M. Pyles, Houston, TX (US);
Inventors:
Ramachandran Radhakrishnan, Fremont, CA (US);
Michael Cyr, League City, TX (US);
Sabine M. Pyles, Houston, TX (US);
Assignee:
Intermune, Inc., Brisbane, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); C07D 211/72 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for synthesizing pirfenidone from bromobenzene having less than about 0.15% by weight dibromobenze is disclosed. Also disclosed are processes of synthesizing pirfenidone without using ethyl acetate or n-butanol, and pirfenidone having controlled levels of ethyl acetate, n-butanol, di(5-methyl-2-pyridinone)benzenes, and other impurities having specified retention times. Also disclosed are formulated dosage forms including the disclosed pirfenidone.