The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2013

Filed:

Sep. 21, 2011
Applicants:

Nicholas Chi-kwan Ling, San Diego, CA (US);

Shui Long Wang, San Diego, CA (US);

Dunrui Wang, San Diego, CA (US);

Sharat Singh, Rancho Santa Fe, CA (US);

Inventors:

Nicholas Chi-Kwan Ling, San Diego, CA (US);

Shui Long Wang, San Diego, CA (US);

Dunrui Wang, San Diego, CA (US);

Sharat Singh, Rancho Santa Fe, CA (US);

Assignee:

Nestec S.A., Vevey, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/531 (2006.01); G01N 33/533 (2006.01); C07K 17/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides novel citrullinated peptides, their use in methods for aiding, assisting, improving, or facilitating the diagnosis or prognosis of rheumatic diseases such as rheumatoid arthritis (RA), and methods for identifying novel citrullinated peptides that are immunoreactive with anti-citrullinated protein antibodies (ACPAs). The present invention also provides methods for detecting rheumatoid factor (RF) using novel RF detection reagents as a means to aid, assist, improve, or facilitate the diagnosis or prognosis of rheumatic diseases such as RA. Kits comprising at least one of the novel citrullinated peptides and/or RF detection reagents of the present invention are also provided.


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