The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2013

Filed:

Jul. 24, 2009
Applicants:

Pei-wen Hsiao, Taipei, TW;

Feng-min Lin, Niaosong Township, Kaohsiung County, TW;

Sheng-yang Wang, Sindian, TW;

Inventors:

Pei-Wen Hsiao, Taipei, TW;

Feng-Min Lin, Niaosong Township, Kaohsiung County, TW;

Sheng-Yang Wang, Sindian, TW;

Assignee:

Academia Sinica, Taipei, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses certain diterpenes that can be used to inhibit androgen receptor activity, induce apoptosis and block cell cycle progression of androgen receptor-dependent cells. Androgen receptor has been associated with various diseases such as prostate cancer, androgeneic alopecia, breast cancer, acne etc. Accordingly, the present invention further discloses methods of treating androgen receptor-associated diseases by administering the disclosed diterpenes.


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