The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2013

Filed:

Sep. 04, 2008
Applicants:

Robert G. Aslanian, Rockaway, NJ (US);

Xianhai Huang, Warren, NJ (US);

Anandan Palani, Bridgewater, NJ (US);

Jun Qin, Edison, NJ (US);

Wei Zhou, Scotch Plains, NJ (US);

Xiaohong Zhu, Edison, NJ (US);

Robert D. Mazzola, Jr., Stewartsville, NJ (US);

Pawan Dhondi, Elizabeth, NJ (US);

William J. Greenlee, Teaneck, NJ (US);

Inventors:

Robert G. Aslanian, Rockaway, NJ (US);

Xianhai Huang, Warren, NJ (US);

Anandan Palani, Bridgewater, NJ (US);

Jun Qin, Edison, NJ (US);

Wei Zhou, Scotch Plains, NJ (US);

Xiaohong Zhu, Edison, NJ (US);

Robert D. Mazzola, Jr., Stewartsville, NJ (US);

Pawan Dhondi, Elizabeth, NJ (US);

William J. Greenlee, Teaneck, NJ (US);

Assignee:

Merck Sharp + Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); C07D 401/12 (2006.01); C07D 237/14 (2006.01); A61K 31/501 (2006.01); A61K 31/50 (2006.01); A61K 31/4439 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's Disease using the compounds of formula (I).


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