The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2013

Filed:

Apr. 18, 2012
Applicants:

Takahiro Honda, Ikoma, JP;

Hisashi Tajima, Ikoma, JP;

Yoshimasa Sasabuchi, Ikoma, JP;

Kenji Kawashima, Ikoma, JP;

Kazuyoshi Okamoto, Ikoma, JP;

Minoru Yamamoto, Ikoma, JP;

Masakazu Ban, Ikoma, JP;

Inventors:

Takahiro Honda, Ikoma, JP;

Hisashi Tajima, Ikoma, JP;

Yoshimasa Sasabuchi, Ikoma, JP;

Kenji Kawashima, Ikoma, JP;

Kazuyoshi Okamoto, Ikoma, JP;

Minoru Yamamoto, Ikoma, JP;

Masakazu Ban, Ikoma, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound having the following formula [I] or a pharmaceutically acceptable salt thereof: wherein A is an aromatic five-membered heterocycle which optionally is fused with a cycloalkane ring; B is an alkylene; Rand Rare hydrogen, hydroxyl, alkoxy, aryloxy, alkyl, cycloalkyl, aryl, heterocycle, amino, alkylamino, arylamino or acyl, or Rand Rjoin together to form a heterocycle; X and Y are hydrogen, halogen, hydroxyl, alkoxy, aryloxy, alkyl, cycloalkyl, aryl, mercapto, alkylthio, arylthio, carboxyl, an ester of carboxyl, an amide of carboxyl, cyano or nitro; p is 0, 1 or 2; and q is 0 or 1. The compound is useful for treating diseases in which angiogenesis or augmentation of vascular permeability is involved.


Find Patent Forward Citations

Loading…