The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2013

Filed:

Nov. 17, 2006
Applicants:

Jean-francois Truchon, Saint-Laurent, CA;

Nicolas Lachance, Pierrefonds, CA;

Cheuk Lau, L'lle Bizard, CA;

Yves Leblanc, Kirkland, CA;

Christophe Mellon, L'lle Bizard, CA;

Patrick Roy, Dollard des Ormeaux, CA;

Elise Isabel, Pointe-Claire, CA;

Ryan D Otte, Newton Centre, MA (US);

Jonathan R Young, Southborough, MA (US);

Inventors:

Jean-Francois Truchon, Saint-Laurent, CA;

Nicolas Lachance, Pierrefonds, CA;

Cheuk Lau, L'lle Bizard, CA;

Yves Leblanc, Kirkland, CA;

Christophe Mellon, L'lle Bizard, CA;

Patrick Roy, Dollard des Ormeaux, CA;

Elise Isabel, Pointe-Claire, CA;

Ryan D Otte, Newton Centre, MA (US);

Jonathan R Young, Southborough, MA (US);

Assignees:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Merck Canada Inc., Quebec, CA;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); A61K 31/444 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides inhibitors of kinases, specifically IκB kinases, JAK1, JAK2, JAK3 and TYK2. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting said kinase activity by administering the compound to a patient in need of treatment for myeloproliferative disorders, cancer or NF-κB-mediated diseases.


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