The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2013

Filed:

Jan. 25, 2006
Applicants:

Robert R. Becklin, Layton, UT (US);

Cindy Lou Chepanoske, Salt Lake City, UT (US);

John M. Peltier, Jefferson, MD (US);

Longwu Qi, West Lafayette, IN (US);

Paul B. Robbins, Park City, UT (US);

Sudhir R. Sahasrabudhe, Sandy, UT (US);

Robert Selliah, Midvale, UT (US);

Keith Simmon, West Valley City, UT (US);

Brent R. Stockwell, New York, NY (US);

Raj Gopal Venkat, Salt Lake City, UT (US);

Moritz Von Rechenberg, Waltham, MA (US);

Eugene Y. Zhen, Carmel, IN (US);

Inventors:

Robert R. Becklin, Layton, UT (US);

Cindy Lou Chepanoske, Salt Lake City, UT (US);

John M. Peltier, Jefferson, MD (US);

Longwu Qi, West Lafayette, IN (US);

Paul B. Robbins, Park City, UT (US);

Sudhir R. Sahasrabudhe, Sandy, UT (US);

Robert Selliah, Midvale, UT (US);

Keith Simmon, West Valley City, UT (US);

Brent R. Stockwell, New York, NY (US);

Raj Gopal Venkat, Salt Lake City, UT (US);

Moritz von Rechenberg, Waltham, MA (US);

Eugene Y. Zhen, Carmel, IN (US);

Assignee:

Prolexys Pharmaceuticals, Inc., Columbia, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); A61K 31/517 (2006.01); C07D 239/72 (2006.01); C07D 401/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to methods of screening for binding partners, especially binding partners essential for the biological activity of erastin (e.g. VDACs such as VDAC3). The invention also provides reagents and methods for effective killing of cancer cells with erastin and related compounds or derivatives.


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