The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2013

Filed:

Feb. 12, 2009
Applicants:

Steven White, San Diego, CA (US);

Erin Olson, San Diego, CA (US);

Keith Lorimer, West Lafayette, IN (US);

Brenton Skylar Wolfe, West Lafayette, IN (US);

Inventors:

Steven White, San Diego, CA (US);

Erin Olson, San Diego, CA (US);

Keith Lorimer, West Lafayette, IN (US);

Brenton Skylar Wolfe, West Lafayette, IN (US);

Assignee:

Harbor Therapeutics, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/567 (2006.01); C07J 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides and describes solid state 17α-ethynyl-5α-androstane-3α,17β-diol including amorphous and crystalline forms and specific polymorphic forms thereof. Anhydrates and solvates of 17α-ethynyl-5α-androstane-3α,17β-diol include Form III anhydrate and Form I solvate. The invention further relates to solid and suspension formulations containing 17α-ethynyl-5α-androstane-3α,17β-diol in a described solid state form and use of the formulations to treat cancers or precancers such as prostate cancer or breast cancer in subjects or human patients. The invention also relates to methods to make liquid formulations from solid state forms of 17α-ethynyl-5α-androstane-3α,17β-diol and uses of such formulations in treating the described conditions.


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