The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 2013

Filed:

Jan. 11, 2012
Applicants:

Thierry Leveillard, Maisons Alfort, FR;

Jose Alain Sahel, Paris, FR;

Saddek Mohand-said, Paris, FR;

David Hicks, Strasbourg, FR;

Inventors:

Thierry Leveillard, Maisons Alfort, FR;

Jose Alain Sahel, Paris, FR;

Saddek Mohand-Said, Paris, FR;

David Hicks, Strasbourg, FR;

Assignees:

Novartis AG, Basel, CH;

Universite de Strasbourg, Strasbourg, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/12 (2006.01); C12N 15/00 (2006.01); C07H 21/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are methods and compositions for early diagnosis, monitoring and treatment of retinal dystrophy, age-related macular degeneration, Bardet-Biedel syndrome, Bassen-kornzweig syndrome, best disease, choroidema, gyrate atrophy, congenital amourosis, refsun syndrome, stargardt disease and Usher syndrome. In particular, the invention relates to a protein, termed 'Rdcvf1,' that is differentially transcribed and expressed in subjects suffering from retinal dystrophies and the like, such as retinal dystrophy and age-related macular degeneration compared with nonsufferers, antibodies which recognize this protein, and methods for diagnosing such conditions.


Find Patent Forward Citations

Loading…