The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2013
Filed:
Sep. 25, 2009
Thomas Baumert, Strasbourg, FR;
Catherine Schuster, Strasbourg, FR;
John Thompson, Freiburg, DE;
Fritz Grunert, Freiburg, DE;
Thomas Baumert, Strasbourg, FR;
Catherine Schuster, Strasbourg, FR;
John Thompson, Freiburg, DE;
Fritz Grunert, Freiburg, DE;
INSERM (Institut National de la Sante et de la Recherche Medicale), Paris, FR;
University de Strasbourg, Strasbourg, FR;
Abstract
The present invention provides monoclonal antibodies that specifically bind to the extracellular domain of human Claudin-1 on the cell surface, thereby inhibiting HCV entry into susceptible cells and preventing HCV infection of these cells; and hybridoma cell lines which produce such monoclonal antibodies. Also provided are reagents that comprise such antibodies, and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing HCV infection by administration of an inventive monoclonal antibody, or a pharmaceutical composition thereof are also described.