The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2013

Filed:

May. 30, 2012
Applicants:

Seok-ki Choi, Ann Arbor, MI (US);

Paul R. Fatheree, San Francisco, CA (US);

Robert Murray Mckinnell, Millbrae, CA (US);

Brooke Olson, San Francisco, CA (US);

Inventors:

Seok-Ki Choi, Ann Arbor, MI (US);

Paul R. Fatheree, San Francisco, CA (US);

Robert Murray McKinnell, Millbrae, CA (US);

Brooke Olson, San Francisco, CA (US);

Assignee:

Theravance, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4184 (2006.01); C07D 235/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to compounds having the formula: wherein Ar, r, n, X, R, R, R, and Rare as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have ATreceptor antagonist activity and neprilysin inhibition activity. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and a process and intermediates for preparing such compounds.


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