The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2013

Filed:

Jul. 25, 2011
Applicants:

Dharma Rao Polisetti, High Point, NC (US);

Suparna Gupta, Greensboro, NC (US);

Inventors:

Dharma Rao Polisetti, High Point, NC (US);

Suparna Gupta, Greensboro, NC (US);

Assignee:

High Point Pharmaceuticals, LLC, High Point, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/426 (2006.01); A61K 31/427 (2006.01); A61K 31/4439 (2006.01); C07D 277/42 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to substituted thiazol-2-ylamine derivatives and pharmaceutically acceptable salts thereof that inhibit 11βHSD1 and that may be useful in the treatment of diseases in which modulation or inhibition of 11βHSD1 is beneficial or where a reduction in intracellular glucorticoid levels is desirable. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases, disorders, or conditions in which modulation or inhibition of 11βHSD1 is beneficial or where a reduction in intracellular glucorticoid levels is desirable.


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