The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2013
Filed:
Sep. 26, 2011
Kwangmeyung Kim, Seoul, KR;
Ick Chan Kwon, Seoul, KR;
Kuiwon Choi, Seoul, KR;
IN Chan Youn, Seoul, KR;
Myungsook Huh, Seoul, KR;
Sojin Lee, Seoul, KR;
Kwangmeyung Kim, Seoul, KR;
Ick Chan Kwon, Seoul, KR;
Kuiwon Choi, Seoul, KR;
In Chan Youn, Seoul, KR;
MyungSook Huh, Seoul, KR;
Sojin Lee, Seoul, KR;
Korea Institute of Science and Technology, Seoul, KR;
Abstract
Disclosed are a human serum albumin-siRNA carrier system having siRNA bound to human serum albumin and a user thereof, and especially, human serum albumin-siRNA carrier system, which has a biodegradable covalent bond between human serum albumin polymer and siRNA and is stable in a living body, and a user thereof. The human serum albumin-siRNA carrier system having the biodegradable covalent bond between the human serum albumin and the siRNA exhibits high siRNA delivery efficiency to a target site in the living body. Therefore, the human serum albumin-siRNA carrier system may allow siRNA for therapy to be efficiently delivered to a target site such as cancer tissues in the living body even by being administrated in a relatively low concentration, which may result in a wide use for therapies of various diseases.