The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2013
Filed:
Jul. 21, 2010
Applicants:
Avijit Chakrabartty, Vaughan, CA;
Rishi Rakhit, Toronto, CA;
Neil R. Cashman, Vancouver, CA;
Inventors:
Assignees:
Amorfix Life Sciences Ltd., Toronto, CA;
University Health Network, Toronto, CA;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 25/02 (2006.01); A61P 25/28 (2006.01); C07K 16/18 (2006.01); C07K 16/40 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides binding proteins that bind to misfolded or monomeric SOD1, and not to native homodimeric SOD1. The invention also includes methods of diagnosing, detecting or monitoring amyotrophic lateral sclerosis in a subject. In addition, the invention provides methods of identifying substances for the treatment or prevention of amyotrophic lateral sclerosis and kits using the binding proteins of the invention.