The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2013
Filed:
May. 04, 2011
Bruce D. Hammock, Davis, CA (US);
Takaho Watanabe, Hadano, JP;
Seung-jin MA, Mokpo, KR;
Susan E. Bennett, Davis, CA (US);
Judith S. Stern, Davis, CA (US);
Christophe Morisseau, West Sacramento, CA (US);
In-hae Kim, Matsuyama-si, JP;
Bruce D. Hammock, Davis, CA (US);
Takaho Watanabe, Hadano, JP;
Seung-Jin Ma, Mokpo, KR;
Susan E. Bennett, Davis, CA (US);
Judith S. Stern, Davis, CA (US);
Christophe Morisseau, West Sacramento, CA (US);
In-Hae Kim, Matsuyama-si, JP;
The Regents of the University of California, Oakland, CA (US);
Abstract
The invention provides uses and methods for reducing nephropathy in persons with diabetes mellitus (particularly Type 2 diabetes), in persons with metabolic syndrome, in persons with triglyceride levels over 215 mg/dL, and in persons with a cholesterol level over 200 mg/dL, by administering an inhibitor of soluble epoxide hydrolase ('sEH'). Optionally, a cis-epoxyeicosantrienoic acid ('EET') can be administered with the sEH inhibitor. The invention further provides for using EETs in conjunction with one or more sEH inhibitors to reduce hypertension, and for compositions of EETs coated with a material insoluble in an acid of pH 3 but soluble in a solution with a pH of 7.4 or higher.