The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2013

Filed:

Jan. 13, 2011
Applicants:

Ajay Gupta, Dollard-des-Ormeaux, CA;

Hyman M. Schipper, Montreal, CA;

Moulay Alaoui-jamali, Laval, CA;

Walter A. Szarek, Kingston, CA;

Kanji Nakatsu, Kingston, CA;

Jason Z. Vlahakis, Kingston, CA;

Inventors:

Ajay Gupta, Dollard-des-Ormeaux, CA;

Hyman M. Schipper, Montreal, CA;

Moulay Alaoui-Jamali, Laval, CA;

Walter A. Szarek, Kingston, CA;

Kanji Nakatsu, Kingston, CA;

Jason Z. Vlahakis, Kingston, CA;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); C07D 233/54 (2006.01); C07D 233/64 (2006.01); C07D 233/56 (2006.01); C07D 233/58 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are compounds of the general formula (I): compositions comprising an effective amount of said compounds either alone or in combination with other chemotherapeutic agents, and methods useful for treating or preventing cancer and for inhibiting tumor tissue growth. These compounds attenuate the oxidative damage associated with increased heme-oxygenase activity and can reduce cell proliferation in transformed cells. In addition, the described compounds and compositions are useful as neuroprotectants and for treating or preventing neurodegenerative disorders and other diseases of the central nervous system.


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