The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2013
Filed:
Sep. 01, 2006
Kleber Gomes Franchini, Campinas, BR;
Mario Jose Abdalla Saad, Campinas, BR;
Roberto Rittner Neto, Campinas, BR;
Rodrigo Miguel Marin, Campinas, BR;
Silvana Aparecida Rocco, Campinas, BR;
Kleber Gomes Franchini, Campinas, BR;
Mario Jose Abdalla Saad, Campinas, BR;
Roberto Rittner Neto, Campinas, BR;
Rodrigo Miguel Marin, Campinas, BR;
Silvana Aparecida Rocco, Campinas, BR;
Universidade Estadual de Campinas-Unicamp, Campinas-SP, BR;
Abstract
The present invention relates to the use of 4-anilinoquinazoline derivatives as adenosine-kinase inhibitors. The present invention also relates to a method for protecting tissues and organs like heart, brain and kidneys affected by ischemia, and for treating heart insufficiency, myocardium infarct, arrhythmia, arterial hypertension, atherosclerosis, coronary artery restenosis after angioplasty, chronic renal insufficiency, cerebral vascular accident, and chronic inflanunatory diseases (e.g., rheumatoid arthritis). The present invention also relates to the compound 6,7-dimethoxy-4-(3'-N′,N′-dimethylaminoanilino)quinazoline, or a pharmaceutically acceptable salt thereof, pharmaceutical composition comprising it and use of such compound in the manufacture of a medicament for treating or preventing diseases or conditions that are benefited from the adenosine-kinase inhibition.