The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2013

Filed:

Mar. 21, 2008
Applicants:

Sonia Escaich, Paris, FR;

Alexis Denis, Paris, FR;

Vincent Gerusz, Paris, FR;

François Moreau, Orsay, FR;

Mayalen Oxoby, Paris, FR;

Yannick Bonvin, St-Germain en Laye, FR;

Inventors:

Sonia Escaich, Paris, FR;

Alexis Denis, Paris, FR;

Vincent Gerusz, Paris, FR;

François Moreau, Orsay, FR;

Mayalen Oxoby, Paris, FR;

Yannick Bonvin, St-Germain en Laye, FR;

Assignee:

Laboratoire Biodim, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61K 31/4985 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to Imidazolo-heteroaryl derivatives of formula (I). The compounds inhibit the activity of the Dlta enzyme of Gram-positive bacteria and are useful to treat Gram-positive bacterial infections. Furthermore the application discloses method for assessing the Dlta inhibitory activity of tested molecules and a method for measuring the efficacy of molecules in inhibiting bacteria proliferation in vitro.


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