The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2013

Filed:

Oct. 11, 2007
Applicants:

Jianhua Shen, Shanghai, CN;

Changlin Mei, Shanghai, CN;

Hualiang Jiang, Shanghai, CN;

Bin Dai, Shanghai, CN;

Yangliang YE, Shanghai, CN;

Xishan Xiong, Shanghai, CN;

Jing Tang, Shanghai, CN;

Lili Fu, Shanghai, CN;

Inventors:

Jianhua Shen, Shanghai, CN;

Changlin Mei, Shanghai, CN;

Hualiang Jiang, Shanghai, CN;

Bin Dai, Shanghai, CN;

Yangliang Ye, Shanghai, CN;

Xishan Xiong, Shanghai, CN;

Jing Tang, Shanghai, CN;

Lili Fu, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/55 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention disclosed compounds of Structural Formula (I), and enantiomer, racemic body, pharmaceutically acceptable salts, solvates or hydrates thereof, wherein variable groups are as defined within, as well as methods for preparing such compounds. The compounds are useful as PPARγ agonist, through activating PPAR-RXR heterodimers that interacts with specific DNA response elements within promoter regions of target gene, particularly in the treatment and prevention of polycystic kidney and cancer.


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