The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 2013

Filed:

Jan. 12, 2007
Applicants:

Haichao Wang, Edison, NJ (US);

Dazhi Chen, Jamaica Estates, NY (US);

Andrew E. Sama, Manhasset, NY (US);

Inventors:

Haichao Wang, Edison, NJ (US);

Dazhi Chen, Jamaica Estates, NY (US);

Andrew E. Sama, Manhasset, NY (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/58 (2006.01); A61K 31/34 (2006.01); A01N 43/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are methods of attenuating release of a proinflammatory cytokine from a mammalian cell. Also provided are methods of inhibiting or treating an inflammatory cytokine cascade in a mammal. Further provided are methods of treating a mammal at risk for or undergoing sepsis, septicemia, and/or endotoxic shock. Additionally provided are methods of attenuating NO release from a mammalian cell. Also provided are methods of attenuating NO production in a mammal at risk for, or having, a disorder mediated by excessive NO production.


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