The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 20, 2013
Filed:
Aug. 09, 2012
Applicants:
Blas Cerda, Milford, MA (US);
Alex Cherkasskiy, West Roxbury, MA (US);
Yijun LI, Worcester, MA (US);
Inventors:
Blas Cerda, Milford, MA (US);
Alex Cherkasskiy, West Roxbury, MA (US);
Yijun Li, Worcester, MA (US);
Assignee:
PerkinElmer Health Sciences, Inc., Waltham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/00 (2006.01); G01N 1/28 (2006.01); G01N 33/48 (2006.01); G01N 33/00 (2006.01); A61K 31/00 (2006.01); A61K 31/70 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention relates, inter alia, to detecting and/or measuring succinylacetone and one or more additional biological analytes using mass spectrometry, e.g., tandem mass spectrometry, by derivatizing succinylacetone in a sample by contacting the sample with an extraction solution comprising a C1-3 linear or branched chain monoalcohol and a strong base selected from the group consisting of hydrazine, a modified hydrazine, and hydroxylamine.