The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 13, 2013

Filed:

Jan. 30, 2009
Applicants:

Tatsuya Matsukawa, Tokyo, JP;

Kazuhiro Masuzaki, Tokyo, JP;

Yosuke Kawai, Tokyo, JP;

Akiko Kawasaki, Tokyo, JP;

Akiko Akasaka, Tokyo, JP;

Makoto Takewaki, Tokyo, JP;

Inventors:

Tatsuya Matsukawa, Tokyo, JP;

Kazuhiro Masuzaki, Tokyo, JP;

Yosuke Kawai, Tokyo, JP;

Akiko Kawasaki, Tokyo, JP;

Akiko Akasaka, Tokyo, JP;

Makoto Takewaki, Tokyo, JP;

Assignee:

R-Tech Ueno, Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/38 (2006.01); A61K 31/427 (2006.01); A61K 31/426 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a thiazole derivative useful as a VAP-1 inhibitor, as well as a pharmaceutical agent for the prophylaxis or treatment of VAP-1 associated diseases and the like, a method of inhibiting VAP-1 in a subject, and a method for the prophylaxis or treatment of VAP-1 associated disease in a subject. The thiazole derivative is a compound represented by the formula (I): R—NH—X—Y—Z wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof.


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