The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2013
Filed:
Jul. 15, 2011
John Richard Nelson, Clifton Park, NY (US);
Robert Scott Duthie, Schenectady, NY (US);
Sonali Jagdish Shah, Avon, CT (US);
Clifford Leslie Smith, Tring, GB;
John Richard Nelson, Clifton Park, NY (US);
Robert Scott Duthie, Schenectady, NY (US);
Sonali Jagdish Shah, Avon, CT (US);
Clifford Leslie Smith, Tring, GB;
General Electric Company, Niskayuna, NY (US);
Abstract
Methods and kits for efficient amplification of nucleic acids are provided. The methods comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having terminal mismatch primer-dimer structure. The methods also comprise in-vitro amplification of a nucleic acid template employing partially constrained primers having nucleotide analogues. The methods enhance efficiency of nucleic acid amplification reaction by reducing non-specific amplification reactions.