The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2013
Filed:
Apr. 01, 2010
Matthieu Guitton, Le Houlme, FR;
Jean-luc Puel, Coumonterral, FR;
Remy Pujol, Montpellier, FR;
Jerome Ruel, Montpellier, FR;
Jing Wang, Lunel, FR;
Matthieu Guitton, Le Houlme, FR;
Jean-Luc Puel, Coumonterral, FR;
Remy Pujol, Montpellier, FR;
Jerome Ruel, Montpellier, FR;
Jing Wang, Lunel, FR;
Auris Medical AG, Lohn-Ammannsegg, CH;
Abstract
The invention relates to methods for the prevention and/or treatment of tinnitus induced by cochlear excitotoxicity. In these methods, a pharmaceutical composition comprising an NMDA receptor antagonist is administered to an individual in need of such treatment by appropriate devices and/or formulations for local administration to the inner ear. The tinnitus to be prevented and/or treated may be provoked by acoustic trauma, presbycusis, ischemia, anoxia, treatment with one or more ototoxic medications, sudden deafness, or other cochlear excitotoxic-inducing occurrence. The invention also relates to method for the identification of compounds effective in the treatment and prevention of tinnitus by a novel screening method incorporating an electrophysiological test method.