The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2013
Filed:
Mar. 20, 2008
Thomas Schultz, Ludwigshafen, DE;
Wilfried Braje, Ludwigshafen, DE;
Sean Colm Turner, Ludwigshafen, DE;
Andreas Haupt, Ludwigshafen, DE;
Udo Lange, Ludwigshafen, DE;
Karla Drescher, Ludwigshafen, DE;
Karsten Wicke, Ludwigshafen, DE;
Liliane Unger, Ludwigshafen, DE;
Mario Mezler, Ludwigshafen, DE;
Matthias Mayrer, Ludwigshafen, DE;
Thomas Schultz, Ludwigshafen, DE;
Wilfried Braje, Ludwigshafen, DE;
Sean Colm Turner, Ludwigshafen, DE;
Andreas Haupt, Ludwigshafen, DE;
Udo Lange, Ludwigshafen, DE;
Karla Drescher, Ludwigshafen, DE;
Karsten Wicke, Ludwigshafen, DE;
Liliane Unger, Ludwigshafen, DE;
Mario Mezler, Ludwigshafen, DE;
Matthias Mayrer, Ludwigshafen, DE;
Abbott GmbH & Co. KG, Wiesbaden, DE;
Abstract
The present invention relates to compounds of formula (I) wherein A is C-C-alkyl, C-C-haloalkyl, C-C-hydroxyalkyl, C-C-alkenyl, C-C-halo-alkenyl, C-C-cycloalkyl, aryl-C-C-alkyl, aryl-C-C-alkenyl, aryl or hetaryl;is a single or double bond; Xand Xare N, CR, NRor CRR; R, Rand Rare H, halogen, CN, NO, C-C-alkyl, C-C-alkoxy, C-C-alkylcarbonyl, etc. or two geminal radicals Rand Rtogether with the carbon atom to which they are bound may form a carbonyl group or a 3- to 6-membered carbocyclic or heterocyclic spiro-annulated ring; Ris hydrogen, C-C-alkyl, C-C-alkylcarbonyl, C-C-haloalkyl, etc.; or two vicinal radicals R, R, Ror Rtogether with Xand Xform a five- or six-membered carbocyclic or heterocyclic fused ring; Y, Yand Yare N or CR; Ris H, halogen, CN, NO, C-C-alkyl, C-C-alkoxy, C-C-alkylcarbonyl, C-C-haloalkyl, etc.; wherein a maximum of 3 of the radicals X, X, Y, Yand Yare selected from NRand N; Ris hydrogen, C-C-alkyl, C-C-hydroxyalkyl, C-C-haloalkyl, etc.; Ris C-C-alkyl or C-C-haloalkyl; n is 0, 1 or 2; physiologically tolerated acid addition salts and the N-oxides thereof, pharmaceutical composition comprising them, a method for treating medical disorders selected from diseases of the central nervous system, addiction diseases or obesity, said method comprising administering an effective amount of such compounds to a subject in need and the use of such a compound for preparing a pharmaceutical compositions.