The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 2013
Filed:
Jul. 14, 2011
Michael D. Kaminski, Lockport, IL (US);
Carol J. Mertz, Downers Grove, IL (US);
Ilya A. Shkrob, Chicago, IL (US);
Mark L. Dietz, Evanston, IL (US);
Cory A. Hawkins, Shorewood, WI (US);
Michael D. Kaminski, Lockport, IL (US);
Carol J. Mertz, Downers Grove, IL (US);
Ilya A. Shkrob, Chicago, IL (US);
Mark L. Dietz, Evanston, IL (US);
Cory A. Hawkins, Shorewood, WI (US);
UChicago Argonne, LLC, Chicago, IL (US);
Abstract
The present invention provides an apparatus and rapid methods for extracting strontium ions from urine to provide a concentrated and purified strontium-90 extract suitable for scintillation measurements. The methods remove organic compounds, pigments, and alkali metal ions that can interfere with quantitative determination of strontium-90 in urine. A method of the invention comprises acidifying urine and removing organic pigments therefrom, loading a known quantity of so-treated urine onto a diphosphonic acid-based ion-exchange resin; flowing aqueous methanesulfonic acid through the diphosphonic acid-based ion-exchange resin to elute alkali metal ions therefrom; eluting strontium ions off of the diphosphonic acid-based resin and on to a strontium extraction chromatographic resin with a concentrated aqueous nitric acid solution; subsequently flowing water or a dilute acid stripping solution through the strontium extraction resin to strip the strontium from the strontium extraction resin; and collecting the strontium-containing stripping solution eluting from the strontium extraction resin.