The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2013

Filed:

Jun. 09, 2011
Applicants:

Marcus F. Boehm, San Diego, CA (US);

Esther Martinborough, San Diego, CA (US);

Manisha Moorjani, San Diego, CA (US);

Liming Huang, San Diego, CA (US);

Junko Tamiya, Oceanside, CA (US);

Mark T. Griffith, San Diego, CA (US);

Thomas Fowler, Melton Mowbray, GB;

Andrew Novak, Nottingham, GB;

Michael Knaggs, Burton-on-Trent, GB;

Premji Meghani, Leicestershire, GB;

Inventors:

Marcus F. Boehm, San Diego, CA (US);

Esther Martinborough, San Diego, CA (US);

Manisha Moorjani, San Diego, CA (US);

Liming Huang, San Diego, CA (US);

Junko Tamiya, Oceanside, CA (US);

Mark T. Griffith, San Diego, CA (US);

Thomas Fowler, Melton Mowbray, GB;

Andrew Novak, Nottingham, GB;

Michael Knaggs, Burton-on-Trent, GB;

Premji Meghani, Leicestershire, GB;

Assignee:

Receptos, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 69/76 (2006.01); A61K 31/235 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds that bind the glucagon-like peptide 1 receptor (GLP-1) receptor are provided including compounds which are modulators of the GLP-1 receptors and compounds which are capable of inducing a stabilizing effect on the receptor for use in structural analyses of the GLP-1 receptor. Methods of synthesis, methods of therapeutic and/or prophylactic use, and methods of use in stabilizing GLP-1 receptor in vitro for crystallization of the GLP-1 receptor of such compounds are provided.


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