The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2013
Filed:
Nov. 19, 2010
Robert Jordan, Thorton, PA (US);
David Knight, Berwyn, PA (US);
Randall Brezski, Spring House, PA (US);
Mary Ryan, Spring House, PA (US);
Diane Petrone, Chesterbrook, PA (US);
Robert Jordan, Thorton, PA (US);
David Knight, Berwyn, PA (US);
Randall Brezski, Spring House, PA (US);
Mary Ryan, Spring House, PA (US);
Diane Petrone, Chesterbrook, PA (US);
Janssen Biotech, Inc., Horsham, PA (US);
Abstract
The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG protease cleavage products to restore effector function to antibody compositions that are subject to protease cleavage.