The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2013
Filed:
Jun. 05, 2009
Elif A. Oral, Ann Arbor, MI (US);
Charles F. Burant, Ann Arbor, MI (US);
Thomas L. Chenevert, Ann Arbor, MI (US);
Hero K. Hussain, Ann Arbor, MI (US);
Barbara J. Mckenna, Ann Arbor, MI (US);
Elif A. Oral, Ann Arbor, MI (US);
Charles F. Burant, Ann Arbor, MI (US);
Thomas L. Chenevert, Ann Arbor, MI (US);
Hero K. Hussain, Ann Arbor, MI (US);
Barbara J. McKenna, Ann Arbor, MI (US);
University of Michigan, Ann Arbor, MI (US);
Abstract
The invention generally relates to the use of leptin in the treatment of a leptin-responsive disease or condition in a non-lipodystrophic subject. More particularly, the invention is directed to the use of leptin in the treatment of a fatty liver disease in a non-lipodystrophic subject with a relative leptin deficiency. The invention includes methods for the treatment of nonalcoholic steatohepatitis (NASH), alcoholic fatty liver disease (AFLD), and nonalcoholic fatty liver disease (NAFLD) in a non-lipodystrophic subject. The invention includes the treatment of conditions ranging from ectopic lipid accumulation (steatosis) to cirrhosis.