The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2013
Filed:
May. 01, 2008
Applicants:
Otto Phanstiel, Iv, Oviedo, FL (US);
Navneet Kaur, Oviedo, FL (US);
Inventors:
Otto Phanstiel, IV, Oviedo, FL (US);
Navneet Kaur, Oviedo, FL (US);
Assignee:
University of Central Florida Research Foundation, Inc., Orlando, FL (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 211/00 (2006.01); C09B 11/02 (2006.01); A61K 38/00 (2006.01); A61K 47/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Several aromatic hydrocarbons di-substituted with a polyamine are described according to formulas selected from compounds 4, 7, 10, 15 and pharmaceutically acceptable salts thereof. The novel dimeric polyamines of the present invention demonstrate enhanced penetration into cells having an upregulated polyamine transport system, such as various types of cancer cells. The disclosed aromatic polyamine dimers provide highly efficient drugs for targeting cancer cells with active polyamine transporters.