The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2013
Filed:
Nov. 12, 2009
Mehul Thathagar, Geleen, NL;
Peter Poechlauer, Linz, AT;
Sascha Braune, Luftenberg an der Donau, AT;
Mehul Thathagar, Geleen, NL;
Peter Poechlauer, Linz, AT;
Sascha Braune, Luftenberg an der Donau, AT;
DSM Fine Chemicals Austria NFG GmbH & Co KG, Linz, AT;
Abstract
A process for the preparation of a cyclopropane derivative of Formula (I), by reacting an olefin of Formula (II), with a carbene of the formula:CRR, in a reaction vessel, optionally in the presence of a solvent, wherein, Rand Rare each independently hydrogen, C-Calkyl, C-Calkenyl, aryl, heteroaryl, heterocyclyl, carbocyclyl, heterocyclyl, —C(O)Ror —NR; R, R, Rand Rare each independently hydrogen, C-Calkyl, C-Calkoxy, C-Calkenyl, aryl, aryloxy, heteroaryl, heterocyclyl, carbocyclyl, heterocyclyl, —C(O)R, —NR, —SR, —S(O)R, or —SOR, or Rand Rare as defined above and Rand Rtogether form a ring, which ring is carbocyclyl, heterocyclyl, aromatic or heteroaromatic; Ris hydrogen, hydroxy, C-Calkyl, C-Calkoxy, aryl, aryloxy, heteroaryl or —NR; Ris hydrogen, C-Calkyl, C-Calkenyl, aryl, heteroaryl, carbocyclyl or heterocyclyl; Ris hydrogen, hydroxy, C-Calkyl, C-Calkoxy, aryl, aryloxy or heteroaryl; Ris hydrogen, C-Calkyl, C-Calkenyl, aryl, heteroaryl, carbocyclyl, heterocyclyl or C(O)R; Ris hydrogen, C-Calkyl, C-Calkenyl, aryl, heteroaryl, carbocyclyl or heterocyclyl; and Ris hydrogen, hydroxy, C-Calkyl, C-Calkoxy, aryl, or aryloxy, in the presence of copper metal or copper oxide, wherein the process is a continuous process.