The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 2013

Filed:

Sep. 14, 2012
Applicants:

Melanie Schultz, Darmstadt, DE;

Kai Schiemann, Jr., Seeheim-Jugenheim, DE;

Wolfgang Staehle, Ingelheim, DE;

Inventors:

Melanie Schultz, Darmstadt, DE;

Kai Schiemann, Jr., Seeheim-Jugenheim, DE;

Wolfgang Staehle, Ingelheim, DE;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4365 (2006.01); A61K 31/423 (2006.01); A61K 31/428 (2006.01); A61K 31/437 (2006.01); A61K 31/4709 (2006.01); A61K 31/444 (2006.01); A61P 19/02 (2006.01); A61P 9/10 (2006.01); A61P 35/02 (2006.01); A61P 27/02 (2006.01); A61P 35/00 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds according to formula (I) as autotaxin inhibitors and the use of such compounds for the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by increased lysophosphatic acid levels and/or the activation of autotaxin, in particular of different cancers.


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