The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 2013

Filed:

Feb. 28, 2011
Applicants:

Éric Marsault, Québec, CA;

Kamel Benakli, Blue Bell, PA (US);

Hamid R. Hoveyda, Brussels, BE;

Mark L. Peterson, Québec, CA;

Sylvie Beaubien, Québec, CA;

Luc Ouellet, Québec, CA;

Carl St-louis, Québec, CA;

Sophie Beauchemin, Québec, CA;

Inventors:

Éric Marsault, Québec, CA;

Kamel Benakli, Blue Bell, PA (US);

Hamid R. Hoveyda, Brussels, BE;

Mark L. Peterson, Québec, CA;

Sylvie Beaubien, Québec, CA;

Luc Ouellet, Québec, CA;

Carl St-Louis, Québec, CA;

Sophie Beauchemin, Québec, CA;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/25 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to novel macrocyclic compounds of formula (I) and their pharmaceutically acceptable salts, hydrates or solvates: wherein R, R, R, R, R, R, n, m, p Z, Z, and Zare as describe in the specification. The invention also relates to compounds of formula (I) which are antagonists of the motilin receptor and are useful in the treatment of disorders associated with this receptor and with or with motility dysfunction.


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